Non-invasive diagnosis of hepatitis B virus-related cirrhosis

Mutations at Nucleotide 1762, 1764 and 1766 of Hepatitis B Virus X Gene in Patients with Chronic Hepatitis B and Hepatitis B-Related Cirrhosis

Abstract       Background and objective: Hepatitis B virus (HBV) is a DNA virus with high tendency toward hepatic tissue. There are currently about 3 million HBV-infected people and 350 to 400 million chronic carriers of this virus in the world. X protein plays a role in the over-expression of oncogenes, carcinogenicity of liver cells and overlaps with the basal co...

Evaluation of miR-101 Level in Patients with Chronic Hepatitis B Virus Infection and Liver Cirrhosis

ABSTRACT        Background and Objective: MiRNAs are small RNAs that are expressed in most eukaryotes, and can regulate gene expression by attaching to the 3’ end of target mRNA. MicroRNA-101 (miR-101) post-transcriptional regulation is important for host-virus interactions. In addition, miR-101 has a tumor suppressive role in liver cancer and metastasis, an...

treatment of hepatitis b virus cirrhosis

Treatment of Hepatitis B Virus Cirrhosis

Article type: Editorial Implication for health policy/practice/research/medical education: Untreated Hepatitis B Virus (HBV) cirrhosis runs a progressive course to liver failure and death. However, new antivirals that adequately control HBV replication can interrupt this ominous clinical course, are capable of reverting liver fibrosis and may avoid liver transplantation. Therefore indefinite tr...

reversibility of hepatitis virus b – induced cirrhosis

reversibility of hepatitis virus b – induced cirrhosis